Description Usage Supplement Facts MELATONIN-SLEEP is a neuro-hormone that is related to a wide range of physiological functions in the human body. Melatonin (N-acetyl-5-methoxytryptamine) is both a neurotransmitter and a hormone that is most known for regulating the body's circadian rhythm ("internal body clock" that regulates the 24-hour cycle of biological processes, including the sleep/wake cycle). Melatonin also works in synch with the neurotransmitter serotonin and both are made from the same chemical precursor. Low levels of melatonin have been associated with depression, fibromyalgia, insomnia, some seizure disorders, etc. Nutramedix utilizes a proprietary extraction and enhancement process that provides a highly bioactive, full spectrum extract. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. SUGGESTED USE For average size adult: put 5 drops under the tongue at bedtime increasing to 10 drops if necessary. Dose can be repeated during the night. It also can be applied topically to the temples during the day or night. Do not use if pregnant or nursing. Stop use if adverse reactions develop. KEEP OUT OF THE REACH OF CHILDREN: Keep tightly closed at room temperature. (59-86F or 15-30C) Contraindications: Melatonin should not be taken by pregnant women or women trying to become pregnant. Nursing women should also avoid taking melatonin supplements. Melatonin interacts with several herbs, especially those that treat insomnia, anxiety and depression. Melatonin also interacts with some prescription medications, can alter blood pressure in some individuals, and can interact with medications used to treat hypertension, or high blood pressure. Anyone on antidepressant medications, especially those affecting serotonin, or SSRI medications, should avoid melatonin supplements or check with their physician. Additionally, Melatonin interacts with steroidal medicines, rendering them useless, so do not take melatonin if you are on prescription steroids. SUPPLEMENT FACTS Serving Size: 15 drops Servings Per Container: 40 INGREDIENT AMT PER SERVING % DAILY VALUE Melatonin 0.5 ml † * % Daily Values are based on a 2,000 calorie diet.† Daily Value not established. Other ingredients: Mineral water, Ethanol (20-24%).