Description Usage Supplement Facts Complete sleep management with neurotransmitter, cytokine, and histamine support* The importance of healthy sleep for overall health and well-being cannot be overstated. Unfortunately, achieving quality sleep is a challenge for many people. Common biological contributors to poor sleep can include physical discomfort, stress, anxiety, high histamine levels, and low levels of sleep-promoting neurotransmitters, such as gamma-aminobutyric acid (GABA). A multifaceted approach is needed to support falling asleep faster, staying asleep longer, and achieving higher quality, more restful sleep. Circadian PM™ utilizes a blend of 10 ingredients, promoting multiple mechanisms of action to nurture healthy sleep. Mechanisms of Action* Calms the central nervous system and promotes sleep initiation by: Increasing GABA, the primary inhibitory central nervous system neurotransmitter* Decreasing breakdown of GABA and its binding capacity* Stimulating GABA receptors* Promotes undisrupted sleep by supporting healthy serotonin levels, leading to increased REM sleep* Reduces wakefulness by supporting healthy histamine levels in the brain* Supports a healthy response to anxiety, promoting better sleep* Promotes normal cytokine function to soothe physical discomfort and support neural cytokine levels* Circadian PM™ features PharmaGABA®, the natural form of GABA, made through a natural fermentation process. This results in a superior form of GABA vs other synthetic options. Synthetic forms of GABA are less bio-available, as their molecular size is too large to pass the blood-brain barrier. PharmaGABA® is easily absorbed and binds to GABA receptors in the peripheral nervous system, activating the parasympathetic nervous system. This activation of the parasympathetic nervous system by PharmaGABA® is measurable within 5 to 30 minutes after ingestion.* The unique blend of herbs, nutrients, and amino acids make Circadian PM™ a must-have formulation for patients dealing with sleep challenges and those who want to improve the quality of their sleep utilizing natural methods. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Suggested Use As a dietary supplement, take 3 capsules once daily before bed, or as directed by your healthcare professional. Do not use while pregnant or nursing. If you are taking medications or have a medical condition, please consult your healthcare practitioner before use. Keep out of the reach of children. Safety-sealed for your protection and for product freshness. Do not use if outer seal is missing or broken. Store in cool, dry place. SUPPLEMENT FACTS Serving Size: 3 capsules Servings Per Container: 30 Ingredients Amount %DV* CalmNight™ BlendGlycine, Valerian Extract (Valeriana officinalis) (root), CurcuWIN™ Turmeric Extract, Lemon Balm Extract (Melissa officinalis) (leaf), Magnolia Extract (Magnolia officinalis) (bark), 5 HTP (5-hydroxytryptophan), L-theanine, PharmaGABA® (Gamma-aminobutyric acid) 2,148 mg † HistaCalm™Black Cumin Extract (Nigella sativa) (seed), Stinging Nettle Extract (leaf) 126 mg † Other Ingredients: Vegetarian cellulose (capsule shell). * % Daily Values are based on a 2,000 calorie diet.† Daily Value not established Manufactured without eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, corn and gluten. Produced in a facility that may process other ingredients containing these allergens.
